Panelists discuss how splice modifiers work by enhancing protein production from the SMN2 gene, with risdiplam (Evrysdi) being an oral daily medication and nusinersen (Spinraza) being administered ...
Although heart cells and skin cells contain identical instructions for creating proteins encoded in their DNA, they're able to fill such disparate niches because molecular machinery can cut out and ...
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Alternative splicing of DOC2A gene shown to drive schizophrenia risk
In an important new study, Chinese researchers have discovered the previously unrecognized role of alternative splicing of ...
Scientists at the Hospital for Sick Children (SickKids) and the University of Las Vegas Nevada (UNLV) have uncovered a genetic link between autism spectrum disorder (ASD) and a rare genetic condition ...
The TP63 gene, an important member of the TP53 family, contains two independent promoters that drive the transcription of TAp63 and ΔNp63, respectively. Through alternative splicing, TAp63 and ΔNp63 ...
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