Coronaviruses evade detection by the host immune system with the help of the endoribonuclease Nsp15, which regulates levels of viral double stranded RNA by cleaving 3′ of uridine (U). While prior ...

DNA DSBs are toxic lesions that are highly detrimental for the maintenance of genomic integrity, holding the potential to generate mutations, copy number alterations and translocations. DSBs are ...

Double-stranded RNA (dsRNA) is a critical immunostimulatory impurity in mRNA production and poses a problem for the downstream purification methods vital to manufacturing mRNA vaccines and ...

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By John Vandermosten, CFA NASDAQ: RNAZ READ THE FULL RNAZ RESEARCH NOTE RNA Oncology Ribonucleic acid (RNA) oncology is a specialized field in the cancer space that focuses on using RNA-based ...

Your DNA is continually damaged by sources both inside and outside your body. One especially severe form of damage called a double-strand break involves the severing of both strands of the DNA double ...

There are plenty of unanswered questions about the origin of life on Earth. But the research community has largely reached consensus that one of the key steps was the emergence of an RNA molecule that ...

We’re celebrating 180 years of Scientific American. Explore our legacy of discovery and look ahead to the future. In 1957, just four years after Francis Crick and other scientists solved the riddle of ...