How does the cell convert DNA into working proteins? The process of translation can be seen as the decoding of instructions for making proteins, involving mRNA in transcription as well as tRNA. But ...

Across all domains of life, immune defenses foil invading viruses by making it impossible for the viruses to replicate. Most known CRISPR systems target invading pathogens' DNA and chop it up to ...

Illinois biochemistry professor Satish Nair and his colleagues discovered a new class of DNA-protein hybrids and determined the mechanisms by which they are formed in bacterial cells. The findings ...

In the early 1980s, David Gilmour, now an emeritus biochemistry and molecular biology professor at Pennsylvania State University, joined the laboratory of geneticist and biochemist John Lis as a ...

RNA transcription is the genomic process in which a cell produces a duplicate of a gene’s DNA sequence. Present in both DNA and RNA sequences, a G-quadruplex (GQ) is a structure of four guanine bases ...

As aging progresses, the quality of DNA and proteins inside cells declines, known to be the cause of various degenerative diseases. However, the connection between aging and RNA has remained largely ...

In a new study, Chinese researchers have discovered the previously unrecognized role of alternative splicing of the DOC2A ...