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Researchers at the Paul Scherrer Institute PSI have developed an AI that could open up a new, cost-effective approach to ...
However, the structure of chromatin also appears to serve a second, possibly more important role, in that it gives eukaryotic cells the capability to exert complex levels of control over gene ...
Inside cells, DNA mixes with proteins to form chromatin within the nucleus. Within chromatin, structures called packing domains form when chromatin fibers fold together. These chromatin packing ...
Inside every human cell, 2 meters of DNA is crammed into a nucleus that is only one-hundredth of a millimeter in diameter.To ...
Varshavsky studied chromatin structure and wanted to develop new methods to detect the DNA-protein interplay in intact cells. Motivated to better understand chromatin structural organization, ...
Researchers found significant differences in genes potentially linked to adult-onset asthma and childhood-onset asthma, with ...
In the cell nucleus, DNA loops around proteins and together they form a thick fiber called chromatin. Genes at the heart of a tight chromatin coil are hard to reach, and thus, essentially inactive.
Using single-cell technologies, the researchers simultaneously analyzed the accessibility of genetic material through chromatin and the actual activity of relevant genes. Their findings reveal a ...
Anyone who's been pleasantly surprised that they can still ride a bike or swim laps after a long hiatus might surmise that ...
Researchers developed a cost-effective assay to be used with chemicals and potential carcinogens associated with reversible ...
Under the agreement, Chromatin Bioscience will use its proprietary chromatinLENS platform to design cell-selective synthetic promoters aligned with Astellas' target profile. The designed promoters ...