Cell signalling pathways are central to maintaining cellular homeostasis and regulating essential functions such as proliferation, apoptosis, and repair. In both cancer and neurodegenerative diseases, ...

In certain contexts, the Notch receptor may participate in “reverse signaling,” influencing neighboring cells directly.

Autophagy is essentially the 'rubbish collection' of our cells. If there are problems in this process, which is so important for our health, diseases such as Parkinson's can result. In their latest ...

Researchers at VIB, Ghent University, and VUB have uncovered how two proteins essential for immune cell development work ...

Study reveals how Golgi proteins GOLPH3 and MYO18A route RTKs to the cell surface, setting oncogenic signaling strength and ...

For most children diagnosed with medulloblastoma, the most common malignant pediatric brain tumor, survival rates are encouraging. But for a subset, remission is not the end of the story. Roughly 30% ...

Calcium is widely known for its role in maintaining strong bones and teeth, but it is also one of the body's most important ...

The distinct aging rates of neural progenitor cells and Wnt signaling dictate mammalian cortical layer proportions.

A team at Huntsman Cancer Institute at the University of Utah (the U) has uncovered a previously unrecognized molecular mechanism by which cells send signals to one another-insight that could help ...

• BTK inhibitors work by targeting and blocking the BTK enzyme, which is crucial for the survival and growth of cancerous B-cells in mantle cell lymphoma (MCL). This cuts off the cancer cell’s support ...