This article introduces the field of bioinformatics and its importance as a cornerstone of biological research, as well as ...

Historical introduction and overview -- Collecting and storing sequences in the laboratory -- Alignment of pairs of sequences -- Introduction to probability and statistical analysis of sequence ...

Bioinformatics researchers who perform alignments of long protein sequences face a difficult choice: They can get accurate results in hours (sometimes days), or quick results if they're willing to ...

The classic methodology of inferring a phylogenetic tree from sequence data is composed of two steps. First, a multiple sequence alignment (MSA) is computed. Then, a tree is reconstructed assuming the ...

Aligning multiple nucleotide sequences is a prerequisite for many if not most comparative sequence analyses in evolutionary biology. These alignments are often recognized as representing the homology ...

Subscribe to our newsletter for the latest sci-tech news updates. Open-access databases such as the European Nucleotide Archive (ENA) contain more than 2.4 million bacterial genomes, and this number ...

Today HPC startup Optalysys announced the successful completion of the Genetic Search System (GENESYS) project with the Earlham Institute. The GENESYS project, which was granted £0.5m in funding from ...

GenAI models have revolutionized bioinformatics applications by learning from massive biological datasets, genomic sequences, protein structures, and single-cell transcriptomes, without requiring ...