Angiotensin II has complex effects on the heart and ... Most important among these are selectivity for the angiotensin type 1 receptor and a lack of agonist activity at this receptor site.

Two groups of drugs, the ACE inhibitors and angiotensin II type 1 receptor antagonists (angiotensin receptor blockers [ARBs]) have been developed with the aim of improving clinical outcomes by ...

Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are a group of drugs used to treat type 2 diabetes and sometimes obesity. GLP-1 RAs are very effective at lowering blood sugar levels.

Erectile dysfunction is rarely a side effect, occurring in less than 1% of patients ... after 2 years on the alpha-blocker Cardura. Drugs known as ARBs (angiotensin II receptor blockers, like ...

Dimerix’s Angiotensin II Type 1 Receptor (AT1R) & Chemokine Receptor 2 (CCR2) Targets for Inflammatory Nephrosis (ACTION) ...

Sparsentan, which in 2023 was approved for IgA nephropathy, is a non-immunosuppressive, oral medication that selectively blocks the angiotensin II type 1 receptor and the endothelin-A receptor to ...

They lower the effect of angiotensin II by blocking the conversion ... inhibitor. GLP-1 receptor agonists offer the following benefits for those with type 2 diabetes and CKD: Lower blood sugar ...