Angiotensin II has complex effects on the heart and ... Most important among these are selectivity for the angiotensin type 1 receptor and a lack of agonist activity at this receptor site.

Candesartan cilexetil (Atacand, Astra Merck), another long-acting nonpeptide antagonist of AT-II type 1 receptors, is a prodrug that is hydrolyzed to its active metabolite candesartan during ...

STOCKHOLM, SE / ACCESS Newswire / May 6, 2025 / Vicore Pharma Holding AB (STO:VICO) ("Vicore"), unlocking the potential of a new class of drug candidates, angiotensin II type 2 receptor agonists ...

Dimerix’s Angiotensin II Type 1 Receptor (AT1R) & Chemokine Receptor 2 (CCR2) Targets for Inflammatory Nephrosis (ACTION) ...

Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu Angiotensin I Asp-Arg-Val-Tyr-Ile-His-Pro-Phe Angiotensin II David W ... it was an endopeptidase or a unique type of exopeptidase that cleaved dipeptide ...

Sparsentan, which in 2023 was approved for IgA nephropathy, is a non-immunosuppressive, oral medication that selectively blocks the angiotensin II type 1 receptor and the endothelin-A receptor to ...

STOCKHOLM, SE / ACCESS Newswire / May 2, 2025 /Vicore Pharma Holding AB (STO:VICO), unlocking the potential of a novel class of drugs, angiotensin II type 2 receptor agonists (ATRAGs), today announced ...