Formins, actin-nucleating proteins that stimulate the de novo polymerization of actin filaments, are important for diverse cellular and developmental processes, especially those dependent on polarity ...
A Novel Mechanism Promotes Actin Patch Formation to Prevent Chromatin Bridge Breakage in Cytokinesis
Chromatin bridges are strands of incompletely segregated DNA connecting the anaphase poles or daughter nuclei. If unresolved, chromatin bridges can break in cytokinesis leading to micronuclei ...
The dynamic processes that occur during the growth of actin, via polymerization, and the breakdown of actin both play significant roles in cellular mechanisms like migration and adhesion. Due to the ...
This is a preview. Log in through your library . Abstract Recessive mutant gene c in ambystoma mexicanum embryos causes a failure of the heart to function even though initial heart development appears ...
Researchers used miniature human brains grown in the lab to uncover why certain genetic mutations lead to abnormally small brains. Changes in actin disrupted the orientation of early brain cell ...
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