The dynamic regulation of chromatin involves four subfamilies of ATP-dependent nucleosome-remodelling complexes: imitation switch (ISWI), chromodomain helicase DNA-binding (CHD), switch/sucrose ...

This study proposes a new mechanism by which Chd1 senses and responds to DNA unwrapping via EDBL engagement to suppress ...

Chromatin remodelers -- protein machines that pack and unpack chromatin, the tightly wound DNA-protein complex in cell ... more details on how a class of ATP-dependent chromatin remodelers ...

Chromatin remodeling ... of ATP, thus capturing the enzyme in action. Methodical data analysis led the researchers to obtain 13 distinct structures of the SNF2H-nucleosome complex at various ...