Back to Healio Drugs that prolong the QT interval may ... and methadone. The 5-HT 3 antagonists have been touted as safe and effective alternatives to droperidol. Many switched from droperidol ...

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14 5-HT 3 receptor antagonists prevent emesis induced by cytostatic drugs that are commonly employed in cancer therapy. 15,16,17 Moreover, based on animal models and preliminary clinical studies ...

Palonosetron (PALO) versus ondanestron/dolasetron (OND/DOL) in preventing chemotherapy-induced nausea and vomiting (CINV) in elderly patients: Combined results from 2 ...

and furthermore had additive effects on the risk for alcohol+drug dependence. It is possible that increased synaptic 5-HT plus increased 5-HT3 receptor responsiveness to 5-HT might result in ...

One agent, aprepitant, is the first member of a new class of antiemetic, the neurokinin type 1 (NK-1) antagonists. The other, palonosetron, is a second-generation 5-HT3 receptor antagonist ...

PATIENTS AND METHODS: We retrospectively studied 58 lung cancer patients given chemotherapy including at least 50 mg/m 2 CDDP with 5-HT 3 receptor antagonists between January 1996 and December 1997.

Evidence supports the idea that antineoplastic drugs and irradiation can initiate ... and the pharmacologic properties of 5-HT 3-receptor antagonists, the oral use of these agents is rational.

Antiemetic drugs are prescription medications that ... antiemetic is ginger (Zingiber officinale). Ginger contains 5-HT3 antagonists known as gingerols. Clinical studies show that ginger may ...

Ondansetron is a selective 5-HT3 receptor antagonist. Serotonin receptors of ... Electrolyte abnormalities, CHF, bradyarrhythmias, concomitant drugs that prolong QT: monitor ECG.

Ondansetron is a selective 5-HT3 receptor antagonist. Serotonin receptors of ... Electrolyte abnormalities, CHF, bradyarrhythmias, concomitant drugs that prolong QT: monitor ECG.