Heliot Ramos, Rafael Devers and Wilmer Flores homered off Nestor Cortes in the first inning and the San Francisco Giants beat San Diego 4-3 to hand the Padres their fourth straight loss.

Heliot Ramos ended a dramatic day in victorious fashion with a big home run in the San Francisco Giants' win Monday night at Petco Park.

Wilmer Flores' two-run shot capped a three-homer first inning for the visiting Giants and Robbie Ray fired 6 2/3 solid innings in San Francisco's 4-3 victory over the San Diego Padres on Monday.

Petco Park’s packed house filled the Gaslamp Quarter with a symphony of boos. Ramos proceeded to troll the Padres fans sitting in the left-field bleachers, pointing and laughing at the Friar faithful. The rest of the night, Ramos was greeted with boos every time he stepped to the plate or fielded a fly ball.

San Diego Padres center fielder Jackson Merrill is out of the Padres lineup against the Giants on Monday after suffering an apparent left ankle injury in Sunday's series finale against the Dodgers.

Dominic Smith hit a three-run single and Drew Gilbert and Tyler Fitzgerald added solo homers as the San Francisco Giants beat the Tampa Bay Rays 7-1.

Nick Pivetta allowed one run in 6 2/3 innings and Ramón Laureano had three of the Padres’ 14 hits as San Diego completed a three-game sweep of the San Francisco Giants with an 11-1 rout.

The Giants came into the week with a prime opportunity to try to claw back into the National League Wild Card race and gain some ground on one of the teams they were trying to chase down in the standings.