Following the game, the 2017 first-round pick delivered a heartfelt message, giving credit to those around him as he reflected on the milestone.

Patrick Mahomes led the Chiefs to a 30-17 win over the Lions.

Mahomes made history on the night, recording 300 career touchdown passes between the regular season and playoffs faster than any other player.

Welcome to the Opening Line, where we look at ways to have a little fun while identifying intriguing early wagers on the upcoming week’s NFL action.

The Washington Commanders will look to keep pace in the NFC East as they host the Chicago Bears for a Monday Night Football showdown.

What channels are NFL games on Sunday? NFL Week 6 schedule with times, how to watch on television, how to stream and what to know about today's games.

Week 6 of the NFL season is the perfect time to take a shot on your favorite players — and Underdog Fantasy is giving fans an easy way to join the action with its Bet $5, Get $100 promo. New users who place just $5 on any NFL Week 6 Pick’em entry will instantly receive $100 in bonus cash,

Sunday also features a must-see matchup between 4-1 teams in Buccaneers vs. 49ers.